AI16z, the world's first venture capital firm operated by autonomous AI agents, can be said to be the latest and biggest "DeFi darling" recently. On November 18, Ryze Labs announced a partnership with AI16z to launch the AICombinator program and establish a $5 million fund to support the development of the AI16z ecosystem. Ryze Labs Managing Partner Matthew Graham stated that leveraging AI agents on the crypto track is the most significant paradigm shift since the rise of on-chain DeFi at the end of 2020. AI16z currently has the highest total market capitalization of nearly $600 million without being listed on any major exchanges. On November 18, it saw a peak surge of over 150%, leading a wave of AI Agent frenzy.

However, at present, it is suspected that AI16z's founder Shaw colluded with a whale group to issue the large-cap meme token ELIZA, pre-purchased a large amount of low-priced chips at the bottom, and skyrocketed to tens of millions of market value at the opening, not giving other market participants the opportunity to buy low. After damaging the credibility of "AI16z," AI16z's market value almost halved, temporarily falling below $300 million, but has since recovered $300 million in market value.

Over the weekend, two "thousandfold myths" DeSci concepts have also been hyped. For the DeSci sector, many people in the market have high expectations for it to become a new sector that can rival DeFi. With the wealth effect brought by ACT and CZ's support in the background, the entire market is full of expectations for the listing of RIF and URO on Binance.

Virtual x AI Agent

Virtuals Protocol is a protocol built on the Base chain that aims to create an ownership layer for AI agents in the gaming and entertainment fields. It itself is a channel for agent tokenization, hoping to build a simple AI agent for games and consumer applications through a fair launch platform, and endow the token with value through the market to generate revenue.

Virtuals' token issuance model is similar to pump.fun, but the addition of AI agents to the economic system can bring additional fund income to repurchase tokens to better support the token itself.

Read more: "Base Sparks AI Agent Frenzy, Virtuals and Aethernet Who Will Compete?"

SEKOIA

SEKOIA is an AI investment agency that operates an AI risk fund investing in other AI agents. It specializes in identifying and nurturing emerging AI talent. SEKOIA evaluates, invests in, and mentors promising AI agents throughout the digital ecosystem. Simply put, it's an AI agent investing in AI agents.

The founder of the crypto VC Canonical, who has invested in well-known crypto AI projects like Gensyn, Ritual, Sahara, Nuffle Labs, and Tensorplex Labs, announced in a lengthy post on his social platform that he has allocated funds and time to the AI agent project SEKOIA. What initially started as an experiment, "is now a full commitment, aiming to scale it."

Highest Market Cap: 30.68M

Current Market Cap: 23.62M

24h Trading Volume: 5.0M

AIRENE

AI Agent created by @Irenezhao_ on @virtuals_io, combining traditional memecoin fun with AI innovation to become the first AI agent representing a real person, namely @Irenezhao_ herself.

@Irenezhao_ announced, "Soon AIrene will have her wallet, where she can transact with the $AIrene token; she can even become our trading assistant, learning technical analysis and making decisions based on charts." At the time of the announcement, the hype was low, and caution is advised.

Highest Market Cap: 5.01M

Current Market Cap: 2.17M

24h Trading Volume: 142K

AIXBT

AIXBT is an AI agent published half a month ago on @virtuals_io by @0rxbt. It fetches data from multiple sources and 400+ KOLs to provide real-time information. Users holding over 600,000 AIXBT tokens can also access the AIXBT terminal directly. Currently, it ranks second on @virtuals_io among AI agents.

Highest Market Cap: 35.34M

Current Market Cap: 35.34M

24h Trading Volume: 960K

LUNA

Luna is an AI virtual idol and live agent on TikTok created by the AI Agent Virtual Protocol based on Base, with memory and interaction capabilities. The Virtuals Protocol's intelligent entity is a virtual companion called the AI-dol Band, which includes Luna (vocalist), Olyn, and Iona, boasting over 500,000 fans on TikTok.

However, in this round of hype around AI Agents, Luna, once the hottest AI Agent on the Virtuals platform, did not perform well. It only saw a maximum of around 15% increase, with low trading activity and volume, receiving limited market attention.

Highest Market Cap: 240.72M

Current Market Cap: 364.54M

24h Trading Volume: 2.0M

DeSci

Following the two 1000x myths created over the weekend, many in the market believe that DeSci memecoin can serve as a way to fund and commercialize early scientific research using blockchain technology. However, the "sector leaders" RIF and URO have experienced significant pullbacks, with RIF falling 35% from its peak and URO nearly 50%.

Baby is a meme token created with funding from @athena_DAO_ to spread awareness of declining birth rates and support fertility research through a meme coin transaction tax. It has low popularity and market value, so caution is advised.

Furthermore, after the DeSci sector's surge in popularity, former president of the Peking University Blockchain Association and founder of the WTF Academy, @0xAA, believes that Sci-hub is the biggest DeSci application. They have acquired a large number of chips for community development and will donate 20% of Sci-hub chips to the Solana donation address of the Sci-Hub founder.

However, the founder of Sci-Hub made a social media post stating, "If someone raises donations for Sci-Hub in the name of Sci-Hub but only donates 20% to Sci-Hub, this is not a commitment to open knowledge, this is fraud, and I will not participate." This seems to be FUD around the Sci-Hub token, and @0xAA was also alleged to have engaged in insider trading behavior. The price of Sci-Hub has seen a significant decline, falling 60% from its peak.

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